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The study examined the mental health and coping mechanisms of undergraduate students during the transition to various learning modes at the University of the Philippines Los Baños. Results showed that female students experienced significantly higher levels of distress than males, whereas no significant differences were found in psychological well being. Coping mechanisms did not differ significantly between the sexes, except for positive reframing. Year-level differences in coping mechanisms were observed for active coping and self-blame. No significant differences in mental health and coping mechanisms were seen across learning delivery modes. Correlation analysis found that only sophomore and senior students show significant relationships between financial status and psychological distress or well-being. Sophomores with high financial status showed increased distress and well-being, while seniors displayed a weak positive correlation between financial status and distress. Moreover, results revealed that freshmen had negative correlations between financial status and planning as well as acceptance. Sophomores exhibited a positive correlation between financial status and humor as a coping mechanism. Junior students displayed moderate positive correlations between income groups and coping mechanisms such as humor, self-blame, and substance use. Senior students with higher financial status demonstrated associations with self-distraction, venting, positive reframing, denial, and avoidant coping. Considering the weak to moderate relationships found, future studies should explore additional variables for a holistic understanding of the correlates of mental health and coping mechanisms among BS Human Ecology students.